Lazio v Zenit St Petersburg, 24 November 2020
| Score | 3-1 to Lazio |
| Referee | Michael Oliver |
| Competition | UEFA Champions League Group F |
| Venue | Stadio Olimpico, Rome |
Kick-off: 9.00pm local
Played behind closed doors due to COVID-19 restrictions.
3 Lazio
Manager: Simone Inzaghi
1 Zenit St Petersburg
Manager: Sergei Semak