Lazio v Borussia Dortmund, 20 October 2020
| Score | 3-1 to Lazio |
| Referee | Clément Turpin |
| Competition | UEFA Champions League Group F |
| Venue | Stadio Olimpico, Rome |
| Attendance | 1,000 |
Kick-off: 9.00pm local
Attendance limited due to COVID-19 restrictions.
3 Lazio
Manager: Simone Inzaghi
1 Borussia Dortmund
Manager: Lucien Favre