Juventus v Villarreal, 16 March 2022
| Score | 3-0 to Villarreal |
| Referee | Szymon Marciniak |
| Competition | UEFA Champions League Round of 16 2nd leg |
| Venue | Allianz Stadium, Turin |
| Attendance | 30,385 |
Kick-off: 9.00pm local
Villarreal won 4-1 on aggregate
0 Juventus
Manager: Massimiliano Allegri
3 Villarreal
Manager: Unai Emery