Galatasaray v Lokomotiv Moscow, 04 November 2021
| Score | 1-1 |
| Referee | Sandro Schärer |
| Competition | UEFA Europa League Group E |
| Venue | Nef Stadium, Istanbul |
| Attendance | 27,776 |
Kick-off: 8.45pm local
1 Galatasaray
Manager: Fatih Terim
1 Lokomotiv Moscow
Manager: Markus Gisdol