Galatasaray v Barcelona, 17 March 2022
| Score | 2-1 to Barcelona |
| Referee | Daniele Orsato |
| Competition | UEFA Europa League Round of 16 2nd leg |
| Venue | Nef Stadium, Istanbul |
| Attendance | 50,110 |
Kick-off: 8.45pm local
Barcelona won 2-1 on aggregate
1 Galatasaray
Manager: Domènec Torrent
2 Barcelona
Manager: Xavi Hernández