FC Porto v Bayer Leverkusen, 04 October 2022
| Score | 2-0 to FC Porto |
| Referee | Anthony Taylor |
| Competition | UEFA Champions League Group B |
| Venue | Estádio do Dragão, Porto |
| Attendance | 42,399 |
Kick-off: 8.00pm local
2 FC Porto
Manager: Sérgio Conceição
0 Bayer Leverkusen
Manager: Gerardo Seoane