Crvena Zvezda v PFC Ludogorets Razgrad, 25 November 2021
| Score | 1-0 to Crvena Zvezda |
| Referee | Jose Sanchez Martinez |
| Competition | UEFA Europa League Group F |
| Venue | Stadion Rajko Mitić, Belgrade |
Kick-off: 6.45pm local
1 Crvena Zvezda
Manager: Dejan Stanković
0 PFC Ludogorets Razgrad
Manager: Stanislav Genchev