Club Brugge v Bayer Leverkusen, 07 September 2022
| Score | 1-0 to Club Brugge |
| Referee | Irfan Peljto |
| Competition | UEFA Champions League Group B |
| Venue | Jan Breydel Stadium, Bruges |
| Attendance | 21,235 |
Kick-off: 9.00pm local
1 Club Brugge
Manager: Carl Hoefkens
0 Bayer Leverkusen
Manager: Gerardo Seoane