Cambridge United v Southampton, 23 August 2022
| Score | 3-0 to Southampton |
| Referee | David Rock |
| Competition | League Cup 2nd round |
| Venue | Abbey Stadium |
| Attendance | 6,733 |
View Cambridge United v Southampton head to head
Kick-off: 7.45pm
3 Southampton
Manager: Ralph Hasenhüttl
Goals:
| Che Adams | 16 |
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| Che Adams | 55 |
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| Dom Ballard | 88 |
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Starting lineup:
Alex McCarthy
Goalkeeper
Jan Bednarek
Defender
Lyanco
Defender
Lewis Payne
Defender
Yann Valery
Defender
Stuart Armstrong
Midfielder
Ibrahima Diallo
Midfielder
Che Adams
Midfielder/Forward
Mohamed Elyounoussi
Midfielder/Forward
Oriol Romeu
Midfielder/Forward
Adam Armstrong
Forward
Substitutions:
| Joe Aribo for Mohamed Elyounoussi | 66 |
| Moussa Djenepo for Adam Armstrong | 66 |
| Sékou Mara for Che Adams | 66 |
| Dom Ballard for Lewis Payne | 75 |
| Diamond Edwards for Ibrahima Diallo | 90 |
Cards:
| Oriol Romeu | 69 | Y |
| Lyanco | 86 | Y |
| Moussa Djenepo | 90 | Y |
On the bench:
Goalkeeper
Willy Caballero
Defender
Mohammed Salisu
Defender
Dynel Simeu
Midfielder
Joe Aribo
Midfielder
Diamond Edwards
Midfielder
Roméo Lavia
Midfielder/Forward
Moussa Djenepo
Forward
Dom Ballard
Forward
Sékou Mara