Brondby v Olympique Lyonnais, 25 November 2021
| Score | 3-1 to Olympique Lyonnais |
| Referee | Georgi Kabakov |
| Competition | UEFA Europa League Group A |
| Venue | Brondby Stadion, Brondbyvester |
Kick-off: 9.00pm
1 Brondby
Manager: Niels Frederiksen
3 Olympique Lyonnais
Manager: Peter Bosz