Bayer Leverkusen v Slavia Praha, 10 December 2020
| Score | 4-0 to Bayer Leverkusen |
| Referee | Tasos Sidiropoulos |
| Competition | UEFA Europa League Group C |
| Venue | BayArena, Leverkusen |
Kick-off: 6.55pm local
4 Bayer Leverkusen
Manager: Peter Bosz
0 Slavia Praha
Manager: Jindřich Trpišovský