Bayer Leverkusen v FC Porto, 12 October 2022
| Score | 3-0 to FC Porto |
| Referee | István Kovács |
| Competition | UEFA Champions League Group B |
| Venue | BayArena, Leverkusen |
| Attendance | 30,210 |
Kick-off: 9.00pm local
0 Bayer Leverkusen
Manager: Xabi Alonso
3 FC Porto
Manager: Sérgio Conceição