Bayer Leverkusen v Atlético Madrid, 21 February 2017
| Score | 4-2 to Atlético Madrid |
| Referee | Willie Collum |
| Competition | UEFA Champions League Round of 16 1st leg |
| Venue | BayArena, Leverkusen |
| Attendance | 29,300 |
Kick-off: 8.45pm local (7.45pm GMT)
2 Bayer Leverkusen
Manager: Roger Schmidt
4 Atlético Madrid
Manager: Diego Simeone