Bayer Leverkusen v AS Roma, 20 October 2015
| Score | 4-4 |
| Referee | Viktor Kassai |
| Competition | UEFA Champions League Group E |
| Venue | BayArena, Leverkusen |
| Attendance | 29,412 |
Kick-off: 8.45pm local (7.45pm BST)
4 Bayer Leverkusen
Manager: Roger Schmidt
4 AS Roma
Manager: Rudi Garcia
Goals:
| Javier Hernández | penalty | 4 |
|
| Javier Hernández | 19 |
|
|
| Kevin Kampl | 84 |
|
|
| Admir Mehmedi | 86 |
|
Goals:
| Daniele De Rossi | 29 |
|
|
| Daniele De Rossi | 38 |
|
|
| Miralem Pjanić | 54 |
|
|
| Iago Falque | 73 |
|
Starting lineup:
Goalkeeper
Bernd Leno
Defender
Giulio Donati
Defender
Ömer Toprak
(captain)
Defender
Kyriakos Papadopoulos
Defender
Jonathan Tah
Defender
Wendell
Midfielder
Karim Bellarabi
Midfielder
Hakan Çalhanoğlu
Midfielder
Kevin Kampl
Midfielder
Christoph Kramer
Forward
Javier Hernández
Starting lineup:
Goalkeeper
Wojciech Szczęsny
Defender
Lucas Digne
Defender
Kostas Manolas
Defender
Antonio Rüdiger
Defender
Vassilis Torosidis
Defender/Midfielder
Alessandro Florenzi
Midfielder
Daniele De Rossi
(captain)
Midfielder
Radja Nainggolan
Midfielder
Miralem Pjanić
Midfielder/Forward
Gervinho
Midfielder/Forward
Mohamed Salah
Substitutions:
| Admir Mehmedi for Karim Bellarabi | 56 |
| Julian Brandt for Christoph Kramer | 66 |
| Vladlen Yurchenko for Ömer Toprak | 79 |
Substitutions:
| Iago Falque for Mohamed Salah | 62 |
| Edin Džeko for Gervinho | 85 |
| Juan Iturbe for Alessandro Florenzi | 90 |
Cards:
| Christoph Kramer | 36 | Y |
| Wendell | 90 | Y |
Cards:
| Radja Nainggolan | 24 | Y |
| Daniele De Rossi | 35 | Y |
On the bench:
Goalkeeper
Dario Kresic
Defender
Sebastian Boenisch
Defender
Tin Jedvaj
Defender
Andre Ramalho
Midfielder
Julian Brandt
Midfielder
Vladlen Yurchenko
Forward
Admir Mehmedi
On the bench:
Goalkeeper
Morgan De Sanctis
Defender
Leandro Castán
Defender
Maicon
Midfielder
Iago Falque
Midfielder
William Vainquer
Midfielder/Forward
Juan Iturbe
Forward
Edin Džeko