Atalanta v Bayer Leverkusen, 10 March 2022
| Score | 3-2 to Atalanta |
| Referee | Srdjan Jovanović |
| Competition | UEFA Europa League Round of 16 1st leg |
| Venue | Gewiss Stadium, Bergamo |
| Attendance | 13,134 |
Kick-off: 9.00pm local
3 Atalanta
Manager: Gian Piero Gasperini
2 Bayer Leverkusen
Manager: Gerardo Seoane