AS Roma v Viktoria Plzen, 24 November 2016
| Score | 4-1 to AS Roma |
| Referee | Tobias Stieler |
| Competition | UEFA Europa League Group E |
| Venue | Stadio Olimpico, Rome |
| Attendance | 13,789 |
Kick-off: 9.05pm local (8.05pm GMT)
4 AS Roma
Manager: Luciano Spalletti
1 Viktoria Plzen
Manager: Roman Pivarnik