AS Roma v Olympique Lyonnais, 16 March 2017
| Score | 2-1 to AS Roma |
| Referee | Viktor Kassai |
| Competition | UEFA Europa League Round of 16 2nd leg |
| Venue | Stadio Olimpico, Rome |
| Attendance | 46,453 |
Kick-off: 9.05pm local (8.05pm GMT)
Olympique Lyonnais won 5-4 on aggregate.
2 AS Roma
Manager: Luciano Spalletti
1 Olympique Lyonnais
Manager: Bruno Génésio