AS Roma v FC Zorya Luhansk, 25 November 2021
| Score | 4-0 to AS Roma |
| Referee | István Kovács |
| Competition | UEFA Europa Conference League Group C |
| Venue | Stadio Olimpico, Rome |
| Attendance | 24,000 |
Kick-off: 9.00pm local
4 AS Roma
Manager: José Mourinho
0 FC Zorya Luhansk
Manager: Viktor Skripnik