AS Roma v Bayer Leverkusen, 04 November 2015
| Score | 3-2 to AS Roma |
| Referee | Sergei Karasev |
| Competition | UEFA Champions League Group E |
| Venue | Stadio Olimpico, Rome |
| Attendance | 38,361 |
Kick-off: 8.45pm local (7.45pm GMT)
3 AS Roma
Goals:
| Mohamed Salah | 2 |
|
|
| Edin Džeko | 29 |
|
|
| Miralem Pjanić | penalty | 80 |
|
Starting lineup:
Goalkeeper
Wojciech Szczęsny
Defender
Kostas Manolas
Defender
Antonio Rüdiger
Defender/Midfielder
Lucas Digne
Defender/Midfielder
Alessandro Florenzi
Midfielder
Daniele De Rossi
(captain)
Midfielder
Radja Nainggolan
Midfielder
Miralem Pjanić
Midfielder/Forward
Gervinho
Midfielder/Forward
Mohamed Salah
Forward
Edin Džeko
Substitutions:
| Maicon for Alessandro Florenzi | 56 |
| Juan Iturbe for Gervinho | 68 |
| Vassilis Torosidis for Maicon | 76 |
Cards:
| Wojciech Szczęsny | 90 | Y |
On the bench:
Goalkeeper
Morgan De Sanctis
Defender
Leandro Castán
Defender
Maicon
Defender
Vassilis Torosidis
Midfielder
Iago Falque
Midfielder
William Vainquer
Midfielder/Forward
Juan Iturbe
Comments:
Group league position: 2nd2 Bayer Leverkusen
Goals:
| Admir Mehmedi | 46 |
|
|
| Javier Hernández | 51 |
|
Starting lineup:
Bernd Leno
Goalkeeper
Giulio Donati
Defender
Ömer Toprak
Defender
(captain)
Kyriakos Papadopoulos
Defender
Jonathan Tah
Defender
Wendell
Defender
Hakan Çalhanoğlu
Midfielder
Kevin Kampl
Midfielder
Javier Hernández
Forward
Stefan Kiessling
Forward
Admir Mehmedi
Forward
Substitutions:
| Karim Bellarabi for Stefan Kiessling | 46 |
| Christoph Kramer for Karim Bellarabi | 73 |
| Julian Brandt for Admir Mehmedi | 88 |
Cards:
| Kyriakos Papadopoulos | 61 | Y |
| Ömer Toprak | 79 | R |
On the bench:
Goalkeeper
Dario Kresic
Defender
Sebastian Boenisch
Defender
Andre Ramalho
Midfielder
Karim Bellarabi
Midfielder
Julian Brandt
Midfielder
Christoph Kramer
Midfielder
Vladlen Yurchenko