AS Roma v Astra Giurgiu, 29 September 2016
| Score | 4-0 to AS Roma |
| Referee | Aliyar Aghayev |
| Competition | UEFA Europa League Group E |
| Venue | Stadio Olimpico, Rome |
| Attendance | 13,509 |
Kick-off: 9.05pm local (8.05pm BST)
4 AS Roma
Manager: Luciano Spalletti
0 Astra Giurgiu
Manager: Marius Sumudica