AS Monaco v Bayer Leverkusen, 27 September 2016
| Score | 1-1 |
| Referee | David Fernández Borbalán |
| Competition | UEFA Champions League Group E |
| Venue | Stade Louis II, Monaco |
| Attendance | 8,100 |
Kick-off: 8.45pm local (7.45pm BST)
1 AS Monaco
Manager: Leonardo Jardim
1 Bayer Leverkusen
Manager: Roger Schmidt