Arsenal v Southampton, 11 December 2021
| Score | 3-0 to Arsenal |
| Referee | Jarred Gillett |
| Competition | Premier League |
| Venue | Emirates Stadium |
| Attendance | 59,653 |
View Arsenal v Southampton head to head
Kick-off: 3.00pm
Premier League Head to Head
Played: 45
Arsenal won: 25
Drawn: 13
Southampton won: 7
Arsenal scored: 85
Southampton scored: 45
Southampton remained without a win in 27 league visits to Arsenal since April 1968.
3 Arsenal
Manager: Mikel Arteta
Goals:
| Alexandre Lacazette | 21 |
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| Martin Odegaard | 27 |
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| Gabriel | 62 |
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Starting lineup:
Goalkeeper
Aaron Ramsdale
Defender
Gabriel
Defender
Ben White
Defender/Midfielder
Thomas Partey
Defender/Midfielder
Kieran Tierney
Defender/Midfielder
Takehiro Tomiyasu
Defender/Midfielder
Granit Xhaka
Defender/Midfielder/Forward
Bukayo Saka
Midfielder
Martin Odegaard
Forward
Gabriel Martinelli
Forward
Alexandre Lacazette
Substitutions:
| Rob Holding for Gabriel | 69 |
| Albert Sambi Lokonga for Granit Xhaka | 81 |
| Nicolas Pépé for Alexandre Lacazette | 83 |
Cards:
| Gabriel | 3 | Y |
| Bukayo Saka | 17 | Y |
On the bench:
Goalkeeper
Arthur Okonkwo
Defender
Cédric Soares
Defender
Rob Holding
Defender
Nuno Tavares
Midfielder
Albert Sambi Lokonga
Midfielder
Emile Smith Rowe
Midfielder/Forward
Ainsley Maitland-Niles
Midfielder/Forward
Nicolas Pépé
Forward
Eddie Nketiah
Comments:
League position: 6th Arsenal avoided losing three consecutive league games for a second time in the same season for the first time since 1983-84 in League Division One. The Gunners had now won three consecutive home games in the Premier League without conceding for the first time since October 2017. 102 goals had now been scored in their 38 games in the Premier League in 2021 (60 for, 42 against). Gabriel scored after 59 minutes but the goal was disallowed after a VAR review due to an offside decision.0 Southampton
Manager: Ralph Hasenhüttl
Goals:
Starting lineup:
Willy Caballero
Goalkeeper
Jan Bednarek
Defender
Jack Stephens
Defender
Tino Livramento
Defender/Midfielder
Kyle Walker-Peters
Defender/Midfielder
Ibrahima Diallo
Midfielder
Nathan Tella
Midfielder
James Ward-Prowse
Midfielder
Nathan Redmond
Midfielder/Forward
Adam Armstrong
Forward
Armando Broja
Forward
Substitutions:
| Mohamed Elyounoussi for Adam Armstrong | 43 |
| Lyanco for Armando Broja | 70 |
Cards:
On the bench:
Goalkeeper
Harry Lewis
Defender
Lyanco
Defender
Yann Valery
Defender/Midfielder
Romain Perraud
Midfielder
Will Smallbone
Midfielder/Forward
Moussa Djenepo
Midfielder/Forward
Mohamed Elyounoussi
Midfielder/Forward
Theo Walcott
Forward
Shane Long