Ajax v Lille OSC, 25 February 2021
| Score | 2-1 to Ajax |
| Referee | Willie Collum |
| Competition | UEFA Europa League Round of 32 2nd leg |
| Venue | Johan Cruyff ArenA, Amsterdam |
Kick-off: 6.55pm local
Ajax won 4-2 on aggregate.
Played behind closed doors due to COVID-19 restrictions.
2 Ajax
Manager: Erik Ten Hag
1 Lille OSC
Manager: Christophe Galtier