Ajax v Beşiktaş, 28 September 2021
| Score | 2-0 to Ajax |
| Referee | Benoît Bastien |
| Competition | UEFA Champions League Group C |
| Venue | Johan Cruyff ArenA, Amsterdam |
| Attendance | 52,628 |
Kick-off: 6.45pm local
2 Ajax
Manager: Erik Ten Hag
0 Beşiktaş
Manager: Sergen Yalçin