1.FSV Mainz 05 v Anderlecht, 20 October 2016
| Score | 1-1 |
| Referee | Jesús Gil Manzano |
| Competition | UEFA Europa League Group C |
| Venue | Opel Arena, Mainz |
| Attendance | 21,317 |
Kick-off: 9.05pm local
1 1.FSV Mainz 05
Manager: Martin Schmidt
1 Anderlecht
Manager: Rene Weiler