Manchester United v Aston Villa, 26 November 1921
| Score | 1-0 to Manchester United |
| Competition | League Division One |
| Venue | Old Trafford |
| Attendance | 40,000 |
View Manchester United v Aston Villa head to head
William Henderson made his debut after moving from Airdrieonians this month. Neil McBain made his debut after moving from Ayr United this month.
Goals:
| William Henderson |
|
Starting lineup:
Goalkeeper
John Mew
Full back
Charles Radford
Full back
John Silcock
Wing half
Frank Harris
Wing half
Neil McBain
Wing half
John Scott
Outside right
William Harrison
Centre forward
William Henderson
Forward
Edward Partridge
Forward
Joe Spence
Inside left
George Sapsford
Goals:
Starting lineup:
Tommy Jackson
Goalkeeper
Ernest Blackburn
Full back
Tommy Smart
Full back
Frank Barson
Centre half
George Blackburn
Left half
Frank Moss
Half back
Arthur Dorrell
Outside left
Richard York
Outside right
Ian William Dickson
Centre forward
Billy Walker
Inside forward
Billy Kirton
Inside right/Outside right